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Click on any ingredient below for details on its purpose.

L-Arginine (AAKG)

L-Arginine

Cardio Miracle™ contains AAKG

A 100% blend of pharmaceutical grade L-arginine and Alpha-Ketoglutrate.

Arginine AAKG gives you all the endothelial- lining-support and vasodilation properties of arginine plus a number benefits from alpha- ketoglutarate (AKG), such as increased arginine stability, bioavailability, and absorption.
Furthermore, alpha-ketoglutarate will serve as a transport medium for arginine, for optimal synthesis. Beyond this, AKG supports the bodies endogenous production of glutamine and glutamic acid, both important for muscle growth and for the immune system. AKG also has been shown to bind to toxic ammonia in muscle cells, in the liver, and in the brain, thereby converting ammonia into glutamic acid improving glutamine levels and assisting in elimination of toxic ammonia from the body. Lastly, as a Krebs Cycle intermediate, AKG has shown to have positive effects on VO2 Max and energy metabolism in muscle cells, and is consequently a potent ergogenic.

Poor absorption can limit L-arginine’s benefits

arginase
Although this powerful Amino Acid has been shown to provide a large number of health benefits, it has one significant issue; our body has a very difficult time digesting and absorbing L-arginine. One reason is that the intestine and liver contain the enzyme arginase that breaks down L- arginine.

Clinical Studies have suggested that in many cases our bodies are able to utilize less than 50% of the L-arginine we consume. The remainder of the L-arginine product is excreted from our body in the form of waste. The low percentage of absorption is what forces hospitals to provide patients with L-arginine intravenously instead of orally. Arginine in the AKG form utilizes a different enzymatic pathway for absorption than regular L-arginine, which allows our body to absorb 90% of the form AKG.

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L-Citrulline

L-Citrulilline
citrulline-nocycle

L-Citrulline is a precursor to arginine in the body. L-citrulline converts to arginine which then converts to Nitric Oxide. L-citrulline is found in watermelon rinds (not as much in the red stuff). Citrulline bypasses the liver and unlike arginine, is not subject to breakdown by arginase. Despite claims that L-citrulline alone is sufficient to raise NO levels this position was contradicted by a 2014 Japanese study that showed the combination of both L-arginine and L-citrulline “raises plasma l-arginine levels, and causes a significantly greater increase in plasma NO and cGMP”nitric-oxide-cycle 


Ornithine

Ornithine is one of the three amino acids involved in the urea cycle. Along with L-arginine and L-citrulline, Ornithine appears to reduce elevated ammonia levels when supplemented; and preliminary evidence suggest an ergogenic role in human health i.e. how products can influence the physical and mental health of people; which has caused a revolution in healthcare.

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AstraGin

AstraGin
AstraGin™ is a proprietary ingredient created by NuLiv Science USA that has been shown to support increased arginine absorption by 67% and l-citrulline absorption by 45%. AstraGin™ is a natural compound composed of highly fractionated astragalus and panax notoginseng. AstraGin™ has been designed and formulated to assist in the overall absorption of the cationic amino acids L-arginine and L-citrulline.

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Fruit, Fiber/Prebiotic & Vegetable Blend – Grape Seed Extract

GrapeSeed
Cardio Miracle utilizes a very high quality grape seed extract with a high concentration of active polyphenols and with antioxidant properties. Grape seed extract helps to support nitric oxide synthase in the endothelium, supporting healthy blood pressure. Grape seed extract is a flavonoid that has a high affinity for collagen structures, including those of your arteries and heart. It is known to support the structural integrity of tissue, helping in some instances to minimize physical wear and tear in the body. Studies may suggest that it may also help strengthen vein health and skin structure.
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Pine Bark

Grape Seed Extract (GSE) and Pine Bark are closely related in terms of their active Proanthocyanidin’s. Each has its merits and so a mixture of three ingredients is used in Cardio Miracle including: Pycnogenol, Pine Bark, and GSE. This creates synergistic benefits. Proanthocyanidin bioflavanoids are virtually identical whether they come from pine bark, grape seeds, lemon tree bark, cranberries, or hazel nut tree leaves. The difference is in the varying concentration in the different plant. GSE has the highest concentration of Proanthocyanidin’s, 95% concentration, and it was selected for use at efficacious levels in Cardio Miracle.

In terms of its use for sustaining beneficial effects the combination of L-arginine and GSE may enhance muscle function and performance; and when combined with other antioxidants like vitamins C and E, and Resveratrol demonstrates synergistic benefits in cardiovascular health.

Among its many benefits in human health GSE, taken along with L-arginine helps to increase nitric oxide production.

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Watermelon Extract

Watermelon
For those who don’t fancy munching on watermelon rind, watermelon extract is an excellent source of L- citrulline, an active precursor to L-arginine. Because it is also rich in lycopene, lutein, and beta carotene, Watermelon has been shown to support increased levels of antioxidants in blood plasma.

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Resveratrol (Polygonum Cuspidatum)

Resveratrol
Resveratrol is found in some red wines and is believed to be a key reason the French can eat high amounts of fat and still maintain a healthy heart. Research shows that Resveratrol can act as a protector against some metabolic stressors associated with a high fat diet. Resveratrol is a potent cardiovascular antioxidant, working synergistically as part of the antioxidant network. It has been shown to enhance the function of an important cellular antioxidant enzyme called MnSOD, which helps support mitochondria to function as it is designed to do.

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Hawthorn Berries

Hawthorn
Hawthorn berries have long been a treatment in botanical medicine for cardiovascular conditions such as high blood pressure. It turns out that much of the benefit derived from hawthorn berries is related to its effect on improving Nitric Oxide production in the nitrite/nitrate pathway.
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Proprietary Blend — Pomegranate fruit extract/beet root crystals

PomogranBlend
Recently, scientists discovered that pomegranate juice may enhance the bioactivity of nitric oxide synthase in endothelial cells. Furthermore, pomegranate’s antioxidant properties help to protect nitric oxide from oxidative destruction. Pomegranate juice has also been shown to support the positive expression of nitric oxide synthase in both healthy and unhealthy blood vessels.
According to a study published in a June 2010 issue of Science Daily, the nitrates in beetroot juice can be beneficial because they have been shown to increase the amount of nitric oxide in the blood and consequently widen blood vessels, support circulation, and support normal blood pressure.
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Fibers

Fiber has a symbiotic relationship with other nutrients that help support healthy cholesterol, cardiovascular health, and maintain a healthy digestive tract. Healthcare professionals are reporting that 75% of people have some form of dysbiosis, or poor gut health. Fiber, taken as a prebiotic, can help alleviate some of those challenges. Not only does Cardio Miracle provide healthy fibers through the organic powders, the product has additional soluble fiber which helps increase nutrient absorption and bulks up the stool which can add benefits for those who may be constipated.

Dietary fibers can act by changing the nature of the contents of the gastrointestinal tract. In particular prebiotic fibers have had a lot of attention recently because healthcare professionals are recognizing how important they are for balance within the human microbiome. Soluble and insoluble fibers encourage healthy flora in the gastrointestinal tract.
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Ionic Trace Minerals

IonicT
Ionic Trace Minerals help to support normal PH balance within the body which facilitates greater absorption of Nitric Oxide. Ionic minerals are easily and quickly absorbed and taken into the cells that line the intestinal tract.
These minerals may are often employed in the body’s many physiologic activities, including nutrient transport, enzyme reactions, metabolism help, and immune system support.
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Vitamin C

VitC
Mothers have been giving Vitamin C to their children ever since Linus Pauling touted its nearly universal benefits. Turns out Mr. Pauling and your mother weren’t wrong; research in this century shows that Vitamin C helps support endothelial Nitric Oxide production. Increased Nitric Oxide levels support healthy endothelial function, and even supports higher l-citrulline levels.
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Vitamin K2 as MK-7

Vitamin K2 optimizes calcium binding to the bone structure, and is an important nutrient to help reduce the potential for the development of osteoporosis. Vitamin K2 is an important ingredient that your body uses to direct calcium to stay in your bones and out of your heart and other body systems. Vitamin K deficiency is a contributing factor in impaired bone strength and mineral density. When calcification takes place in the blood vessels’ they can become stiff and fragile which can impede healthy blood flow to and from the heart.
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Vitamin D3

VitD3

Vitamin D is sometimes called the sunshine vitamin. Studies show that moderate sun exposure will increase the body’s natural vitamin D, providing a boost in energy and a feeling of well-being. Some research has suggested that this may be because of vitamin D’s role in Nitric Oxide production. Studies may suggest that insufficient vitamin D may reduce the bioavailability of Nitric Oxide in veins and arteries. The CDC reports that vitamin D deficiency has risen to 25% of the population. Many researchers believe this deficiency may contribute to increases in blood pressure and cardiovascular disease risk. One serving of Cardio Miracle helps support normal vitamin D levels associated with optimal Nitric Oxide production.
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Vitamin B Complex

VitB1

Besides helping sustain normal metabolic function the B vitamins play an important role in regulating homocysteine levels in the blood. A New York study showed that homocysteine levels greater than 1200 microM “produced significant indirect suppression of eNOS activity.” The B vitamin group also helps regulate other chemicals that directly affect mitochondrial activity believed to eventually induce NO synthesis.
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Vitamin B6

VitB6

Magnesium is involved in many vital biochemical reactions. It has an anti-arrhythmic effect and can influence blood pressure levels. Improving magnesium levels can also help improve the production and release of nitric oxide.
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Vitamin B12 (Cyanocobalamin)

VitB12

There is evidence that zinc deficiency can disrupt endothelial cell function and increase oxidative damage. Zinc is consequently important in maintaining the Nitric Oxide cycle.Back to list.


Natural Vitamin E (as gamma tocopherol)

VitE

Vitamin E, and especially Vitamin E expressed as gamma tocopherol, is a potent antioxidant and provides Nitric Oxide support. Vitamin E helps support the minimization of cell-damaging free radicals on the endothelial lining thus and has been shown to support higher levels of nitric oxide.Back to list.


Other Ingredients — Stevia / natural flavors

Cardio Miracle’s sugar-free formula is sweetened with Stevia; no Xylitol, aspartame, or Sucralose. Our naturally sweetened formula contains organic cane sugar. Compared to white sugar, organic cane sugar has the full-bodied taste of sugarcane and is much less processed, retaining a lot of the nutrients present in cane juice. Unrefined cane sugar contains 17 amino acids, 11 minerals, and 6 vitamins, including antioxidants that may help reverse oxidative damage.Back to list.