Nitric Oxide’s Effect On Coronavirus
The symptoms of the new variant of the coronavirus, more popularly known as COVID-19,seems to be the same of the common flu only with an additional symptom of a loss of smell. However, some people experiencing this latest variant of the coronavirus have inexplicably experienced stronger respiratory distress than one would experience with other flu strains. In addition, there seems to be some confusion over the hypoxic state some patients experienced, flooding emergency rooms in New York just after the first shut down of the country was ordered on March 13th, 2020. Government officials believed the country was on the verge of a fast spreading little known flu that would take the lives of millions of Americans.
More is being discovered weekly but there seems to be controversy over those admitted to emergency rooms in a totally hypoxic state and those that experienced the symptoms of the common flu in conjunction with respiratory distress. For those patients in respiratory distress, Italian doctors experimented with inhaled nitric oxide together with vitamin C in the early phase of the Corona outbreak with great success. For the patients in a hypoxic state they were put on ventilation respirators and most died. Doctors admit that had they understood those patients were hypoxic they wouldn’t have put them on respirators. Not knowing what they were dealing with at the time they little other options and unfortunately this resulted in the deaths of many.
It appears this new coronavirus variant accelerates dysfunction of the inner lining of the arterial wall which then produces nitric oxide deficiency. The arterial inner lining is smooth tissue called the endothelium which releases the vasodilator and antithrombotic factor, nitric oxide. Nitric oxide is a critical gas that is produced in the lining of the arterial wall and is responsible for dilation of the vessels and increasing blood flow and oxygenation to the entire body. Decreased amounts of nitric oxide contribute to high blood pressure, thrombus formation and spells disaster for any person in respiratory distress.
While many are asymptomatic and most experience light symptoms it is known that those who experience severe symptoms are on average 80 years of age according to Italian data. And the CDC, Center For Disease Control, stated that 94% of all deaths in the United States between Feb. 1- Aug. 2 were people who had 2.6 commorbidities. So, this closely mirrors the Italian data as well. In other words, people that are having severe reactions are people that are severely immunocompromised with, on average, almost three other serious diseases. Those people afflicted with atherosclerosis, diabetes, COPD, heart disease and metabolic syndrome are at greater risk of having a more difficult time shaking off this flu. These adults can experience a stronger reaction to the coronavirus and experience clotting in their blood vessels, which can lead to heart attacks or strokes. The clotting seems to be linked to a malfunctioning endothelium and normally prevents clotting according to Frank Ruschitzka, a cardiologist at the University Hospital Zurich in Switzerland.
Problems with the endothelium seem to be involved in most of the advanced cases of the new variant of the coronavirus that progress to severe or fatal disease in adults, Ruschitzka says. However, endothelium is typically in much better condition in children than adults. Children’s endothelium is set up perfectly and then deteriorates with age.
Many doctors believe that because children have much healthier endotheliums and optimal levels of nitric oxide they are less likely to become infected. Children make up only a small proportion of those infected by SARS-CoV-2, the virus that causes this new variant of the coronavirus, AKA COVID-19.
A large survey by the US Centers for Disease Control and Prevention in Atlanta, Georgia, found that children aged 17 and under, who make up 22% of the US population, account for fewer than 2% of confirmed coronavirus infections across the United States. And, of 2,572 children included in the survey, only 5.7% went to hospital and only three died.
According to Åke Lundkvist, a professor at Uppsala University who lead a study on nitric oxide published in the journal, Redox Biology,
"To our knowledge, nitric oxide is the only substance shown so far to have a direct effect on SARS-CoV-2."
Based on a report of improved lung function during the 2003 SARS outbreak due to nitric oxide inhalation, FDA’s emergency response expanded use of nitric oxide gas and is now underway for treating this new variant of the coronavirus.
In an effort to aid the immune system naturally, it is strongly suggested to include in the diet green vegetables in order to increase nitric oxide production. It is well understood that dietary nitrates are converted to nitric oxide through a series of steps beginning with the friendly microflora on the tongue. Here, it converts nitrate to nitrite and then reduced to nitric oxide in the gut, blood stream and various organs, including the lungs. Nitric oxide not only restores endothelial function but also boosts the immune system while promoting antimicrobial and antiviral activity.
Dietary inorganic nitrate has been shown in multiple studies to be effective at restoring endothelial function, reducing pulmonary and arterial hypertension, and promoting antimicrobial activity
Reportedly, consumption of inorganic nitrate for 8 days in COPD population increased lung nitric oxide by 200% and reduced respiratory symptoms. Nitric oxide has been used for well over a decade to help the body not only kill off virus in the lungs but to restore oxygen efficiency and decrease inflammation to those experiencing pulmonary distress.
Restoring nitric oxide through supplementation is an excellent way for those over the age of 30 to gain improved nitric oxide function in addition to eating a healthy diet. This is one more natural method to increase the body’s immunity and fight off all viruses and pathogens.